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Online Resumes with "small molecule inhibitor"
I am seeking opportunities to contribute as a scientist within preclinical drug development or drug discovery research for the bio-pharmaceutical industry to support the primary or secondary screening and characterization of the molecular mechanism of action of lead drug candidates enabling target validation. I specialize in the development of cell-based assays using genomic, proteomic and biochemical approaches implementin...
Tags for this Online Resume: Lentiviral Retroviral shRNA RNA knockdown screens, Flow Cytometry, RTPCR, Immunopreciptations, Reporter assays, Cell based Assays, ELISA, Migration, Stable and Transient Transfections, Genomic and Proteomic Studies, Cloning, Transient siRNA knockdowns, Phenotyping Mammalian cell lines, Gene Overexpression, Subcloning to expression Vectors, Construct Stable Inducible Cell lines, Protein Kinase Assay, Pulse Chase Experiments, Transfection, Transduction, Transformation, Polyoma virus DNA tumor virus replication, Research Scientist, Cell Biology Protein Biochemistry Genetics Molecular Bioliogy Oncology Virology, FACS
Cell & Molecular Biologist with proven expertise in areas such as preclinical research on cell & molecular biology, oncology, biochemistry, discovery of novel tumor suppressor, cancer cell signaling, protein purification & characterization, tissue culture, western blot, ELISA, flow cytometry, live cell imaging, identification of prognostic marker for detecting aggressively proliferating colonic adenoma, identifying new drug...
Accomplished and dedicated scientist focusing on signaling pathway related to tumor angiogenesis and cancer biology area with 15 years' of proven effectiveness in publishing top tier journals (Science, Cancer Cell, PNAS, JCI, Blood etc.) in related research area and in context with identifying and validating novel signaling in tumor angiogenesis, tumor metastasis and retinal angiogenesis areas. Well-versed in applying novel...
Tags for this Online Resume: Foster City, Basic research, Recombinant DNA, Protein expression in different systems and Purification , Mice tumor studies, Cell Culture, Grant writing and IACUC protocols preparation, Eesearch Data presentation and research articles preparation
Summary: Molecular Biologist with expertise in highly driven research environment experience ranging from writing grant proposal, MTAs with pharmaceutical companies, planning experiments, wet bench laboratory techniques, data collection, analysis, writing articles for publication in journals, preparation and presentation at National and International meetings to teaching and training students and fellows and supervising tec...
Tags for this Online Resume: Oncology, Research, Cancer, Pharmaceutical, Translation research, Medical writing, liaison, Management, Senior scientist, Clinical scientist, CRA, scientist, oncology, cancer research, medical liaison
Summary of Qualifications Highly skilled and experienced Senior Research Investigator acknowledged for a strong background in Cell Biology, Immunology, Oncology. Expertise with target identification and validation of small molecule inhibitors on autoimmune disease and multiple cancers with the skill sets in receptor biology, signal transduction, Molecular Biology, and in vivo Mouse Models. Provide excellent communication sk...
PROFILE Result oriented team player with a strong expertise in medicinal/organic chemistry and successful track record in product development, project management, manufacturing support and new projects initiation. Career Highlights * Worked on syntheses of various receptors agonists for the diseases associated with metabolic disorders and ions imbalance * Identified RDX98940, gut-restricted TGR5 agonist, as development cand...
PROFESSIONAL SUMMARY * Highly motivated and versatile scientist with experience in in vitro/cell-based assay development, validation and execution, in vivo pharmacology, including 5+ years of industry experience * Extensive experience in discovery and development of small molecule inhibitors against protein homeostasis * Expertise in defining strategy and providing leadership in various aspects of in vivo POC, target identi...
Tags for this Online Resume: drug discovery, in vitro/cell-based assay development, in vivo pharmacology, RT-PCR/q-PCR, Protein Biochemistry, PD biomarker, CRO expereince, program management, PK/PD relationship, disease animal models, mammalian/primary/cancer/iPS cell culture, co-cultures